Description
Allopurinol, an isomer of hypoxanthine, is the drug of choice in hyperuricemia and gout. This blocks the production of uric acid by inhibiting Xanthine Oxidase and eventually prevents gout. Apart from this, it is also considered an antimetabolite. Often given to the patients going through the chemotherapy to avoid uric acid synthesis from nucleotides of dying cells.
BASIC INFO.:
- Model number:
- CAS number: 315-30-0
- Name: Allopurinol.
- Trademark:
- Specifications: Xanthine Oxidase inhibitor used to treat gout and hyperuricemia.
- Mf:
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PRODUCT SPECIFICATIONS:
- Treatment and Function: Xanthine oxidase inhibition leads to reduced uric acid production.
- Physical Form: Fluffy white to off-white powder.
- Medicine Type: Human Medicine.
- Ingredients: Allopurinol API
- Recommended for: gout, tumor lysis syndrome, kidney stones, and hyperuricemia.
- Storage: Store in a tightly-closed container at room temperature but at a secure place.
USES:
Allopurinol uses include gout, hyperuricemia, calcium oxalate kidney stones, and tumor lysis syndrome. In all these conditions, the goal is to limit the production of uric acid by blocking the xanthine oxidase enzyme. Other than this, allopurinol can also be used in inflammatory bowel disease but to a limited extent only. There are also some speculations that this agent can be helpful in some psychiatric conditions.
CHEMICAL COMPOSITION:
Allopurinol, a bicyclic structure with a pyrazole ring, is a structural isomer of hypoxanthine. Its IUPAC name is 1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one. The chemical formula for this drug is C5H4N4O.
PRODUCT APPLICATION:
Since allopurinol is a structural isomer of hypoxanthine, it binds to the xanthine oxidase enzyme and blocks it. The result is reduced synthesis of uric acid and hence it finds its use in the management of gout, hyperuricemia, and tumor lysis syndrome. Kidney stones can also be prevented and treated by it. Although uric acid stones are better treated with it, yet allopurinol can be used to deal with calcium stones.
PHYSICAL AND CHEMICAL PROPERTIES:
- Melting Point – >300℃
- Density – 1.7±0.1g/cm3
- Form – Crystalline Powder.
- HS Code – 30049099
- Color – Fluffy White to Off-white.
- Molecular Weight – 136.11g/mol
- Solubility – Soluble in water.
