FOR SAMPLE & CONSULTANCY

    Fungi grow not only on rotting organic foods and substances but also on and in humans. When providing a niche to the fungi, the human body gets sick, and their functionality is compromised. These sicknesses and infections require to be treated. Ketoconazole is a drug with antifungal properties and manages various sorts of fungal infections. THYKN Pharma Outsourcing is a well-known supplier of these extraordinary drug APIs.

    COMMON USES OF KETOCONAZOLE:

    • Athlete Foot.
    • Jock’s Itch.
    • Tinea.
    • Ringworm.
    • Dandruff/Seborrhic Dermatitis.
    • Candidiasis.
    • Blastomycosis.
    • Histoplasmosis.
    • Coccidioidomycosis.
    • Chromomycosis.
    • Paracoccidioidomycosis.

    STORAGE OF KETOCONAZOLE:

    Ketoconazole is sensitive to moisture and needs to be stored somewhere far from the humidity at a temperature range of 15-25℃.

    Category:

    Description

    Ketoconazole is one of the drugs from the famous antifungal azole group. This drug is very competent in protecting humans against fungus but rarely utilized. Its limited use is because of the anti-androgenic effects on the human body. These side effects can sometimes be employed for human use, for example, in managing alopecia and Cushing’s syndrome.

    BASIC INFO.:

    • Model number:
    • CAS number: 65277-42-1
    • Name: Ketoconazole.
    • Trademark:
    • Specifications: An azole antifungal drug with anti-androgenic actions.
    • Mf:
    • MOQ:
    • Sample:
    • Transport Package:
    • Original:

    PRODUCT SPECIFICATIONS:

    • Treatment and Function: Antifungal drug used to manage ringworm, athlete’s foot, jock’s itch, dandruff, candidiasis, blastomycosis, etc.
    • Physical Form: Colorless crystals or powder.
    • Medicine Type: Human Drugs.
    • Ingredients: Ketoconazole API.
    • Recommended for: Patient having fungal infection resistant to other medications.
    • Storage: Ketoconazole should be stored at moderate room temperature in a tightly sealed container in a dry environment.

    USES:

    Ketoconazole has two types of actions; antifungal and anti-androgenic. Antifungal uses include ringworm, athlete’s foot, jock’s itch, candidiasis, tinea versicolor, coccidioidomycosis, chromomycosis, etc. The anti-androgenic actions are utilized in the management of Cushing’s Syndrome and Alopecia.

    CHEMICAL COMPOSITION:

    The Molecular formula for this drug is C26H28Cl2N4O4, whereas the IUPAC name for this ketoconazole is 1-[4-[4-[[2-(2,4-dichlorophenyl)-2-(imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]ethenone.

    PRODUCT APPLICATION:

    When you look at the azole antifungals, they are very much similar to imidazole. Like other azoles, ketoconazole blocks the synthesis of ergosterol in the fungi. This cholesterol-like compound is necessary for the maintenance of the fungal membranes, and its absence causes the fungal cells to die. The action of inhibiting ergosterol synthesis makes it a fantastic drug for fungal infections.

    PHYSICAL AND CHEMICAL PROPERTIES:

    • Melting Point – 146℃
    • Density – 1.4±0.1g/cm3
    • Form – Crystals/Powder.
    • HS Code – 29332990/29335990
    • Color – Colorless.
    • Molecular Weight – 531.43g/mol
    • Solubility – Practically insoluble in water.

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