Description
Metoclopramide is a Paraminobenzoic Acid-derived prokinetic drug that can inhibit nausea and vomiting. It increases the forward motility of the gut and facilitates gastric emptying. This gut stimulant is widely used in the treatment plans of various stomach problems in which the gut muscles have reduced activity. Its actions are not only limited to humans but can also exert similar effects on animals.
It is a centrally acting antiemetic because of its direct impact on the chemoreceptor trigger zone of the brain.
BASIC INFO.:
- Model number:
- CAS number: 364-62-5
- Name Metoclopramide.
- Trademark:
- Specifications: A prokinetic and antiemetic drug for both humans and animals.
- Mf:
- MOQ:
- Sample:
- Transport Package:
- Original:
PRODUCT SPECIFICATIONS:
- Treatment and Function: It is a prokinetic and antiemetic drug used in conditions of nausea, vomiting, gastroparesis, etc.
- Physical Form: White Powder
- Medicine Type: Human and Veterinary Drug.
- Ingredients: Metoclopramide API.
- Recommended for: People suffering from gastroparesis, vomiting, nausea, chemotherapy, radiotherapy, etc.
- Storage: Store this drug in a light-resistant container at room temperature.
USES:
This prokinetic drug is utilized in nausea and vomiting as it prevents them from happening by increasing the forward motility of the gut. In addition, because of the stimulating action, it is used in diabetic gastroparesis, a condition in which bowel activity is diminished. It has the same actions in animals.
Besides, it is used in the management of gastric bezoars and GERD. Sometimes, it can also be used to deal with Migraine.
CHEMICAL COMPOSITION:
Metoclopramide has an IUPAC name, 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide. The chemical formula for this substance is C14H22ClN3O2.
PRODUCT APPLICATION:
The action of this drug in preventing vomiting and curing nausea is because of its ability to block dopamine and serotonin receptors in the chemoreceptor trigger zone of the brain. Additionally, the prokinetic tendencies of this drug are the consequence of its agonizing action on the muscarinic and specific serotonin receptors and antagonizing action on the dopamine receptors. The collective response of this action on the gut is that the bowel activity is enhanced. Therefore, it is used in conditions like diabetic gastroparesis.
PHYSICAL AND CHEMICAL PROPERTIES:
- Melting Point – 147.3℃
- Density – 1.2±0.1g/cm3
- Form – Solid.
- HS Code – 29420090/30033900
- Color – White.
- Molecular Weight – 299.80g/mol
- Solubility – Soluble in water.