FOR SAMPLE & CONSULTANCY

    All across the globe, millions of people suffer from erectile dysfunction. To deal with this condition, a very renowned drug is used, and is it called Sildenafil. The famous brand name by which it is known is Viagra. THYKN Pharma Outsourcing is an excellent source that supplies Sildenafil API or Sildenafil Citrate API.

    COMMON USES OF SILDENAFIL:

    • Erectile Dysfunction.
    • Pulmonary Hypertension.

    STORAGE OF SILDENAFIL:

    This drug should be stored in a sealed container at temperatures below 30℃. Heat and Moisture should be avoided.

    Category:

    Description

    Sildenafil is a phosphodiesterase-5 inhibitor drug and is known by the name of Viagra all across the globe. This compound is a pyrazolopyrimidinone derivative and functions by causing dilation of the blood vessels, particularly in the penis. It must be used very carefully and by the prescription of doctor as it has some mild to severe side effects.

    BASIC INFO.:

    • Model number:
    • CAS number: 139755-83-2
    • Name: Sildenafil.
    • Trademark:
    • Specifications: Phosphodiesterase-5 inhibitor agent that causes vasodilation and prolonged erection.
    • Mf:
    • MOQ:
    • Sample:
    • Transport Package:
    • Original:

    PRODUCT SPECIFICATIONS:

    • Treatment and Function: It is used in the treatment of erectile dysfunction and pulmonary hypertension because of its ability to dilate the blood vessels.
    • Physical Form: White to Off-White Crystalline Powder.
    • Medicine Type: Human drug.
    • Ingredients: Sildenafil API
    • Recommended for: Persons suffering from erectile dysfunction or pulmonary hypertension.
    • Storage: This should be stored in a container below 30℃.

    USES:

    Owing to its ability to dilate the blood vessels in the penis, this compound is used to treat erectile dysfunction. In some patients with pulmonary hypertension, this drug is utilized to dilate the pulmonary vessels as well.

    CHEMICAL COMPOSITION:

    IUPAC name for sildenafil is 5-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonylphenyl]-1-methyl-3-propyl-6H-pyrazolo[4,3-d]pyrimidin-7-one. The chemical formula is C22H30N6O4S.

    PRODUCT APPLICATION:

    A phosphodiesterase-5 inhibitor works by blocking this enzyme in the vascular smooth muscles. Normally, PDE-5 is involved in the diminishing of cGMP which promotes vasodilation under the influence of nitric oxide. When sildenafil blocks PDE-5, the cGMP concentration increases, and vasodilation happens. This enhances the blood flow. In the penis, it is used to treat erectile dysfunction while in the lung, pulmonary hypertension is managed by this drug.

    PHYSICAL AND CHEMICAL PROPERTIES:

    • Melting Point – 189-190℃.
    • Density – 1.4±0.1 g/cm3
    • Form – Crystalline Powder.
    • HS Code – 29350090.
    • Color – White to Off-White.
    • Molecular Weight – 474.6g/mol
    • Solubility – It is sparingly soluble in water.

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