Valsartan, a renowned blood pressure-lowering drug, belongs to the class of medications called Angiotensin II Receptor Blockers. This medication is widely used to treat hypertension. THYKN Pharmaceuticals is a well-known supplier of valsartan globally.

COMMON USES OF VALSARTAN:

This drug can be used to manage following diseases;

  • Hypertension
  • Myocardial Infarction
  • Chronic kidney disease
  • Diabetic Vasculopathies

STORAGE OF VALSARTAN:

Valsartan should be stored in a dry place at room temperature 15-30°C away from light.


Description

Valsartan is an orally active nonpeptide triazole, which blocks the angiotensin ll receptors. It is used as an anti-hypertensive in humans and animals to manage proteinuria and hypertension in cats and dogs. This drug controls high blood pressure and related complications such as heart diseases, stroke, and renal problems and reduces mortality after a heart attack.

BASIC INFO.:

  • Model number:
  • CAS number: 137862-53-4
  • Name: Valsartan.
  • Trademark:
  • Specifications: An efficacious anti-hypertensive agent.
  • Mf:
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  • Sample:
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PRODUCT SPECIFICATIONS:

  • Treatment and Function: Acts on angiotensin 2 Receptor causing vascular smooth muscle relaxation, thus lowering blood pressure and preventing hypertensive emergency and complications.
  • Physical Form: White Powder.
  • Medicine Type: Human and Veterinary Drug.
  • Ingredients: Valsartan API.
  • Recommended for: Hypertension in Humans, Cats, and Dogs.
  • Storage:  Store it in a dry and well-ventilated place at room temperature.

USES:

Valsartan effectively reduces high blood pressure and is universally used to treat hypertension. It is also used to prevent stroke, myocardial infarction, and diabetic nephropathy. Its use is limited to vessels and related complications. In addition to the benefits mentioned above, Valsartan also reduces ventricular remodeling in MI patients, thus reducing mortality.

CHEMICAL COMPOSITION:

The IUPAC name of valsartan is (2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid. The chemical formula is C24H29N5O3.

PRODUCT APPLICATION:

Valsartan belongs to the angiotensin receptor blockers (ARBs) group of drugs and is a competitive antagonist at the AT1 receptor. Valsartan relaxes vascular smooth muscles by preventing angiotensin-mediated vasoconstriction. This action results in lowering blood pressure. It also reduces blood pressure by inhibiting the aldosterone secretion from the adrenal gland. This drug also inhibits AT1 receptors in adrenal glands.

PHYSICAL AND CHEMICAL PROPERTIES:

  • Melting Point –116-117 °C
  • Density –1.2±0.1g/cm3
  • Form – Powder
  • HS Code – 30049079/29332990
  • Color – White
  • Molecular Weight- 435.5 g/mol
  • Solubility – Valsartan is freely soluble in methanol and ethanol, whereas sparingly soluble in water. It is 0.18g/L soluble in water at 25°C.