Colchicine is a therapeutic agent usually used in the management of acute gout. This drug belongs to the anti-gout class of drugs and should be used very carefully. Because of its very narrow therapeutic index, colchicine is prescribed very carefully and long-term use is not appreciated.

COMMON USES OF COLCHICINE:

  • Gout.
  • Behcet’s Disease.
  • Familial Mediterranean Fever.
  • Scleroderma.
  • Sarcoidosis.

STORAGE OF COLCHICINE:

Colchicine is sensitive to light and darkens on exposure to light. It should be kept in tight-closed containers away from light at room temperature.


Description

Colchicine belongs to a group of medicines that are given in the management of gout. It is not indicated for the treatment of gout as it does not inhibit the disease progression but it certainly reduces the pain and joint swelling. Therefore, it is given in acute attacks of gout. In older times, the plant from which it is extracted was used to manage the joint swellings.

BASIC INFO.:

  • Model number:
  • CAS number: 64-86-8
  • Name: Colchicine.
  • Trademark:
  • Specifications:
  • Mf:
  • MOQ:
  • Sample:
  • Transport Package:
  • Original:

PRODUCT SPECIFICATIONS:

  • Treatment and Functions: Used in the treatment of gout, Behcet’s disease, and some other conditions.
  • Physical Form: White to Pale Yellow Powder/Scales.
  • Medicine Type: Human
  • Ingredients: Colchicine API
  • Recommended for: Humans suffering from gout and Behcet’s disease.
  • Storage: Store in airtight containers and protect it from the light.

USES:

Colchicine is a very effective agent in reducing joint pain and swelling induced by gout. Familial Mediterranean Fever and Behcet’s Disease are some other indications for the use of colchicine.

CHEMICAL COMPOSITION:

Chemically, colchicine is N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide and has Carbon, Hydrogen, Oxygen, and Nitrogen. Its chemical formula is C22H25NO6.

PRODUCT APPLICATION:

Colchicine is used in gout because of its ability to limit the inflammatory process hence, reducing the pain. Due to this action of colchicine, various conditions that causes widespread inflammation are involved in the indications of colchicine. It controls the inflammation by affecting the molecular mechanism that induces inflammation. Behcet’s disease and Familial Mediterranean fever are conditions in which multiple tissues of the body are facing inflammation. Colchicine is used to stop this inflammation.

PHYSICAL AND CHEMICAL PROPERTIES:

  • Melting Point – 153-157℃
  • Density – 3±0.1g/cm3
  • Form – Powders or Scales.
  • HS Code –
  • Color – White, Off-White, and Pale Yellow.
  • Molecular Weight – 437g/mol.
  • Solubility – Soluble in Water.