Diabetes Mellitus is a global illness that has affected millions of people and is still rising. Multiple drugs have been introduced for the management of this life-limiting illness. Glibenclamide, also known as glyburide, belongs to sulfonylureas and is one of the common drugs available to deal with diabetes. THYKN Pharma Outsourcing is determined to supply high-quality API of Glibenclamide worldwide. 

COMMON USES OF GLIBENCLAMIDE:

The only use of this drug is in diabetes mellitus type 2. This miraculous drug is all about lowering the blood glucose levels in patients suffering from type 2 DM. Patients with type 1 DM are not supposed to use this. Cerebral edema is another condition in which Glibenclamide can be utilized.

STORAGE OF GLIBENCLAMIDE:

Glibenclamide is a heat-sensitive drug and should be stored away from heat at room temperature in a perfectly closed container.


Description

Belonging to the class of sulfonylureas, Glibenclamide is a drug that is slanted towards dealing with diabetes mellitus. This drug aims to reduce blood sugar levels by increasing insulin concentration in the body. It is not used in type 1 DM because there is no insulin to release in such patients. In addition to type 2 DM, cerebral edema can also be reduced by this drug.

BASIC INFO.:

  • Model number:
  • CAS number: 10238-21-8
  • Name: Glibenclamide.
  • Trademark:
  • Specifications: An oral hypoglycemic.
  • Mf:
  • MOQ:
  • Sample:
  • Transport Package:
  • Original:

PRODUCT SPECIFICATIONS:

  • Treatment and Function: It reduces blood sugar levels and is used in type 2 diabetes mellitus.
  • Physical Form: White Powder.
  • Medicine Type: Human Drugs.
  • Ingredients: Glibenclamide API.
  • Recommended for: Type 2 diabetic people.
  • Storage: Store it in a closed container at room temperature, away from heat.

USES:

A hypoglycemic drug means a drug that reduces the blood levels of glucose. Glibenclamide is an oral hypoglycemic, and for this reason, it is used in the management of type 2 diabetes mellitus. Occasionally, it can be used to lower cerebral edema. 

CHEMICAL COMPOSITION:

The IUPAC name for Glibenclamide is 5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide. The molecular formula for this compound is C23H28ClN3O5S.

PRODUCT APPLICATION:

This drug works by promoting insulin release by the pancreas in the body. This insulin then causes the excess sugar in the blood to get into the cells and be utilized effectively. This compound increases the insulin release by binding to the sulfonylurea receptor subunit and boosts the process of calcium entering the pancreatic cells and insulin coming out of these cells.

PHYSICAL AND CHEMICAL PROPERTIES:

  • Melting Point – 169℃
  • Density – 1.4±0.1g/cm3
  • Form – Powder.
  • HS Code – 29242190
  • Color – White.
  • Molecular Weight – 494.00g/mol
  • Solubility – Insoluble in water.