Diuretics are drugs that increase the excretion of water from the body in the form of urine. They are of various types, but the one under discussion is Hydrochlorothiazide. This drug is used in managing hypertension and edema. THYKN Pharma Outsourcing supplies elite quality API of this drug all across the globe reliably. 

COMMON USES OF HYDROCHLOROTHIAZIDE:

  • Hypertension.
  • Edema due to heart failure.
  • Edema due to hepatic cirrhosis.
  • Edema due to nephrotic syndrome and other kidney conditions.
  • Diabetes Inspidus.
  • Renal Tubular Acidosis.
  • Kidney stone prevention in patients with hypercalcemia.

STORAGE OF HYDROCHLOROTHIAZIDE:

It must be stored in a cool, dry place in a tightly closed container.


Description

Hydrochlorothiazide is a diuretic drug with applications in a number of conditions. This short-acting diuretic drug is a benzothiadiazine derivative. It lowers blood pressure in hypertensive patients and diminishes the level of edema in patients suffering from heart, liver, and kidney conditions. 

BASIC INFO.:

  • Model number:
  • CAS number: 58-93-5
  • Name: Hydrochlorothiazide.
  • Trademark:
  • Specifications: An diuretic drug with actions in hypertension and edema.
  • Mf:
  • MOQ:
  • Sample:
  • Transport Package:
  • Original:

PRODUCT SPECIFICATIONS:

  • Treatment and Function: A diuretic drug used to manage edema and hypertension.
  • Physical Form: Crystalline White Powder.
  • Medicine Type: Human Drugs.
  • Ingredients: Hydrochlorothiazide API.
  • Recommended for: Patients with hypertension and edema secondary to various conditions.
  • Storage: Place it in a cool, dry place.

USES:

Hydrochlorothiazide is used alone or in combination with other drugs to lower blood pressure. Additionally, this drug is frequently used to treat edema secondary to various conditions like heart failure, nephrotic syndrome, cirrhosis, etc. Furthermore, conditions like Diabetes insipidus and renal tubular acidosis also come under this agent’s therapeutic effect.

CHEMICAL COMPOSITION:

The molecular formula for this diuretic is C7H8ClN3O4S2. IUPAC name for this drug is 6-chloro-1,1-dioxo-3,4-dihydro-2H-1λ6,2,4-benzothiadiazine-7-sulfonamide.

PRODUCT APPLICATION:

The diuretic action of this drug is because of its action on the proximal segments of distal convoluted tubules of the kidney. Here it blocks the sodium chloride symporter and prevents the reabsorption of these ions back into the blood. As a result, the reabsorption of water is also inhibited and is excreted in the urine. The consequence of this elimination of water is reduced blood volume and lower blood pressure. This way also helps remove the excess fluid from the edema sites. 

PHYSICAL AND CHEMICAL PROPERTIES:

  • Melting Point – 266-268℃
  • Density – 1.7±0.1g/cm3
  • Form – Crystalline Powder.
  • HS Code – 29349900
  • Color – White.
  • Molecular Weight – 297.7g/mol
  • Solubility – Slightly soluble in water.