The human body is not only liable to viruses or bacteria, but it is also to fungi as well. To deal with this type of infection, drugs of different types are there. Itraconazole is an example of antifungal medicine. With a broad spectrum of actions against different fungi, itraconazole is an excellent fungicidal drug. THYKN Pharma Outsourcing supplies itraconazole worldwide with the promise of fine quality.

COMMON USES OF ITRACONAZOLE:

  • Aspergillosis.
  • Histoplasmosis.
  • Coccidioidomycosis.
  • Blastomycosis.
  • Paracoccidiodomycosis.
  • Onychomycosis.

STORAGE OF ITRACONAZOLE:

Itraconazole is sensitive to light and heat, so it is better to store this compound in a setting away from light and heat. It is advised to store it in a well-ventilated, dry place at 15-25℃.


Description

Itraconazole belongs to the azole group of antifungals and is used to manage a wide range of fungal infections in immunecompromised and completely healthy individuals. Conditions like blastomycosis, histoplasmosis, etc., respond better to this drug. This drug can be consumed via oral as well as an intravenous route for systemic and superficial fungal infections.

BASIC INFO.:

  • Model number:
  • CAS number: 84625-61-6
  • Name: Itraconazole.
  • Trademark:
  • Specifications: An azole antifungal to treat various fungal infections.
  • Mf:
  • MOQ:
  • Sample:
  • Transport Package:
  • Original:

PRODUCT SPECIFICATIONS:

  • Treatment and Function: An antifungal drug that is used in the management of histoplasmosis, blastomycosis, aspergillosis, etc.
  • Physical Form: White powder.
  • Medicine Type: Human Drugs.
  • Ingredients: Itraconazole API.
  • Recommended for: Patients suffering from any kind of fungal infection.
  • Storage: Store it at 15-25℃, and protect it from light and heat.

USES:

The fungus-killing action of itraconazole is phenomenal and is used in the management of some serious pulmonary as well as extra-pulmonary histoplasmosis, aspergillosis, blastomycosis, coccidioidomycosis, etc.

CHEMICAL COMPOSITION:

Itraconazole’s IUPAC name is 2-butan-2-yl-4-[4-[4-[4-[[(2R,4S)-2-(2,4-dichlorophenyl)-2-(1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazin-1-yl]phenyl]-1,2,4-triazol-3-one. The molecular formula for this compound is C35H38Cl2N8O4.

PRODUCT APPLICATION:

As all other azoles works, itraconazole works by weakening the membrane of the fungi. Fungal membranes require ergosterol for them to be strong enough. Itraconazole blocks the synthesis of this compound in the fungi, weakening the cellular membrane and increasing cell membrane permeability. This action compromises fungal survival. It also blocks some steps of energy metabolism in the fungi.

PHYSICAL AND CHEMICAL PROPERTIES:

  • Melting Point – 166.2℃
  • Density – 1.4±0.1g/cm3
  • Form – Powder.
  • HS Code – 29333990
  • Color – White.
  • Molecular Weight – 705.64g/mol
  • Solubility – Insoluble in water.